Highlights & Publications
- Feinberg MA, Le MT, Carpio KL, Knyazhanskaya E, Barrett ADT, Choi KH. “Interaction of West Nile virus NS5 with orthoflavivirus SLA RNAs and their effects on viral replication and inhibition.” Journal of virology 2025 Sep 23 ;99(9):e0202324 link
- Berger S, Lee EF, Harris TJ, Tran S, Bera AK, Arguinchona L, Kang A, Sankaran B, Kasapgil S, Miller MS, Smyth S, Lutfi M, Uren RT, Kluck RM, Colman PM, Fairlie WD, Czabotar PE, Baker D, Birkinshaw RW. “Computational design of potent and selective binders of BAK and BAX.” Science advances 2025 Sep 05 ;11(36):eadt4170 link
- Nguyen BV, Özden C, Dong K, Koc OC, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankara S, Abromson NL, Tomchick DR, Fissore RA, Chen J, Garman SC, Stratton MM. “A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.” Nature communications 2025 Sep 26 ;16(1):8461 link
- Ralston CY, Gupta S, Del Mundo JT, Soe AC, Russell B, Rad B, Tyler J, Paul S, Kahan DN, Kristensen LG, Subramanian S, Kidd S, Burnett K, Sankaran B, Classen S, Prigozhin DM, Taylor JR, Dickert JM, Royal KB, Rozales A, Ortega SL, Allaire M, Nix JC, Hura GL, Holton JM, Hammel M, Adams PD. “ALS-ENABLE: creating synergy and opportunity at the Advanced Light Source synchrotron structural biology beamlines.” Journal of synchrotron radiation 2025 Jul 01 ;32(Pt 4):1059-1067 link
- Khmelinskaia A, Bethel NP, Fatehi F, Mallik BB, Antanasijevic A, Borst AJ, Lai SH, Chim HY, Wang JY’, Miranda MC, Watkins AM, Ogohara C, Caldwell S, Wu M, Heck AJR, Veesler D, Ward AB, Baker D, Twarock R, King NP. “Local structural flexibility drives oligomorphism in computationally designed protein assemblies.” Nature structural & molecular biology 2025 Jun ;32(6):1050-1060 link
- Rambo RP, Tainer JA. “Information Theory Optimization of Signals from Small Angle Scattering Measurements.” Biophysical journal 2025 Jun 27 link
- Longo MA, Ahmed SM, Chen Y, Tsai CL, Namjoshi S, Shen R, Ahmed Z, Wang X, Perera RL, Arvai A, Lee M, Kong LR, Engl W, Ng WS, Zhao ZW, Venkitaraman AR, Tainer JA, Schlacher K. “BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability.” Molecular cell 2025 Jun 05 ;85(11):2080-2096.e6 link
- Gupta K, Sekulić N, Allu PK, Sapp N, Huang Q, Sarachan K, Christensen M, Lund R, Krueger S, Curtis JE, Gillilan RE, Van Duyne GD, Black BE. “Solution conformational differences between conventional and CENP-A nucleosomes are accentuated by reversible deformation under high pressure.” Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2025 Jun 12 ;33(1):11 link
- Eneli A, Wang K, Gan J, Diwan R, Lu Z, Yu M, Ackermann R, Shay B, Schwendeman A. “A Comparative Study on Physicochemical and Analytical Characterizations of Doxil® and its Generic Drug Products.” The AAPS journal 2025 Jun 02 ;27(4):100 link
- Arkinson C, Dong KC, Gee CL, Costello SM, Soe AC, Hura GL, Marqusee S, Martin A. “NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome.” Nature structural & molecular biology 2025 Apr 11 link
- Lee S, Kibler RD, Ahn G, Hsia Y, Borst AJ, Philomin A, Kennedy MA, Huang B, Stoddard B, Baker D. “Four-component protein nanocages designed by programmed symmetry breaking.” Nature 2025 Feb ;638(8050):546-552 link
- Patt E, Classen S, Hammel M, Schneidman-Duhovny D. “Predicting RNA structure and dynamics with deep learning and solution scattering.” Biophysical journal 2025 Feb 04 ;124(3):549-564 link
- Brosey CA, Shen R, Tainer JA. “NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism.” The EMBO journal 2025 Feb ;44(4):1220-1248 link
- Cory SA, Lin CW, Patra S, Havens SM, Putnam CD, Shirzadeh M, Russell DH, Barondeau DP. “Frataxin Traps Low Abundance Quaternary Structure to Stimulate Human Fe-S Cluster Biosynthesis.” Biochemistry 2025 Feb 18 ;64(4):903-916 link
- Gan J, Juang V, Wang K, Xia Z, Ackermann R, Yu M, Dorsey KH, Lin W, Wang X, Wang Y, Liang J, Zheng J, Xu X, Park JH, Schwendeman A. “Reverse engineering of Onivyde® – Irinotecan liposome injection.” International journal of pharmaceutics 2025 Jan 25 ;669:125000 link
- Botting JM, Rahman MK, Xu H, Yue J, Guo W, Del Mundo JT, Hammel M, Motaleb MA, Liu J. “FlbB forms a distinctive ring essential for periplasmic flagellar assembly and motility in Borrelia burgdorferi.” PLoS pathogens 2025 Jan 08 ;21(1):e1012812 link
- Berndsen CE, Storm AR, Sardelli AM, Hossain SR, Clermont KR, McFather LM, Connor MA, Monroe JD. “The Pseudoenzyme β-Amylase9 From Arabidopsis Activates α-Amylase3: A Possible Mechanism to Promote Stress-Induced Starch Degradation.” Proteins 2025 Jan 23 link