Highlights & Publications 2018
- Lo YH, Pillon MC, Stanley RE. “Combining X-Ray Crystallography with Small Angle X-Ray Scattering to Model Unstructured Regions of Nsa1 from S. Cerevisiae.” Journal of visualized experiments : JoVE 2018 Jan 10 link
- Walker RG, McCoy JC, Czepnik M, Mills MJ, Hagg A, Walton KL, Cotton TR, Hyvönen M, Lee RT, Gregorevic P, Harrison CA, Thompson TB. “Molecular characterization of latent GDF8 reveals mechanisms of activation.” Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 30 ;115(5):E866-E875 link
- Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, Tainer JA, Phillips GN, Kurie JM. “Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.” Nature communications 2018 Feb 06 ;9(1):512 link
- Chang A, Abderemane-Ali F, Hura GL, Rossen ND, Gate RE, Minor DL. “A Calmodulin C-Lobe Ca2+-Dependent Switch Governs Kv7 Channel Function.” Neuron 2018 Feb 21 ;97(4):836-852.e6 link
- Banerjee R, Yoder JB, Yue DT, Amzel LM, Tomaselli GF, Gabelli SB, Ben-Johny M. “Bilobal architecture is a requirement for calmodulin signaling to CaV1.3 channels.” Proceedings of the National Academy of Sciences of the United States of America 2018 Mar 27 ;115(13):E3026-E3035 link
- Ogorzalek TL, Hura GL, Belsom A, Burnett KH, Kryshtafovych A, Tainer JA, Rappsilber J, Tsutakawa SE, Fidelis K. “Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy.” Proteins 2018 Mar ;86 Suppl 1(Suppl 1):202-214 link
- Johnson CN, Potet F, Thompson MK, Kroncke BM, Glazer AM, Voehler MW, Knollmann BC, George AL, Chazin WJ. “A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel.” Structure (London, England : 1993) 2018 May 01 ;26(5):683-694.e3 link
- Zettl T, Das R, Harbury PAB, Herschlag D, Lipfert J, Mathew RS, Shi X. “Recording and Analyzing Nucleic Acid Distance Distributions with X-Ray Scattering Interferometry (XSI).” Current protocols in nucleic acid chemistry 2018 Jun ;73(1):e54 link
- Remesh SG, Armstrong AA, Mahan AD, Luo J, Hammel M. “Conformational Plasticity of the Immunoglobulin Fc Domain in Solution.” Structure (London, England : 1993) 2018 Jul 03 ;26(7):1007-1014.e2 link
- Zhang S, Zhou P, Wang P, Li Y, Jiang L, Jia W, Wang H, Fan A, Wang D, Shi X, Fang X, Hammel M, Wang S, Wang X, Zhang L. “Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein.” Cell reports 2018 Jul 10 ;24(2):441-452 link
- Ramadan AM, Daguindau E, Rech JC, Chinnaswamy K, Zhang J, Hura GL, Griesenauer B, Bolten Z, Robida A, Larsen M, Stuckey JA, Yang CY, Paczesny S. “From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.” JCI insight 2018 Jul 26 ;3(14):e99208 link
- Caviness P, Bauer R, Tanaka K, Janowska K, Roeser JR, Harter D, Sanders J, Ruth C, Matsushita O, Sakon J. “Ca2+ -induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation.” The FEBS journal 2018 Sep ;285(17):3254-3269 link
- Li Q, Gakhar L, Ashley Spies M. “Determinants of human glucokinase activation and implications for small molecule allosteric control.” Biochimica et biophysica acta. General subjects 2018 Sep ;1862(9):1902-1912 link
- Pham VV, Salguero C, Khan SN, Meagher JL, Brown WC, Humbert N, de Rocquigny H, Smith JL, D’Souza VM. “HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry.” Nature communications 2018 Oct 15 ;9(1):4266 link
- Tang HYH, Shin DS, Hura GL, Yang Y, Hu X, Lightstone FC, McGee MD, Padgett HS, Yannone SM, Tainer JA. “Structural Control of Nonnative Ligand Binding in Engineered Mutants of Phosphoenolpyruvate Carboxykinase.” Biochemistry 2018 Dec 04 ;57(48):6688-6700 link
- De-la-Torre P, Choudhary D, Araya-Secchi R, Narui Y, Sotomayor M. “A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15.” Biophysical journal 2018 Dec 18 ;115(12):2368-2385 link
- Schneidman-Duhovny D, Hammel M. “Modeling Structure and Dynamics of Protein Complexes with SAXS Profiles.” Methods in molecular biology (Clifton, N.J.) 2018 ;1764:449-473 link
- Cho C, Chande AT, Gakhar L, Hunt J, Ketterer MR, Apicella MA. “Characterization of a nontypeable Haemophilus influenzae thermonuclease.” PloS one 2018 ;13(5):e0197010 link
- Moiani D, Ronato DA, Brosey CA, Arvai AS, Syed A, Masson JY, Petricci E, Tainer JA. “Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities.” Methods in enzymology 2018 ;601:205-241 link