Highlights & Publications 2020

READ
READ
READ
READ
READ
  1. Herrmann J, Li PN, Jabbarpour F, Chan ACK, Rajkovic I, Matsui T, Shapiro L, Smit J, Weiss TM, Murphy MEP, Wakatsuki S. “A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly.” Proceedings of the National Academy of Sciences of the United States of America 2020 Jan 07 ;117(1):388-394 link
  2. Gao ZZ, Wang ZK, Wei L, Yin G, Tian J, Liu CZ, Wang H, Zhang DW, Zhang YB, Li X, Liu Y, Li ZT. “Water-Soluble 3D Covalent Organic Framework that Displays an Enhanced Enrichment Effect of Photosensitizers and Catalysts for the Reduction of Protons to H2.” ACS applied materials & interfaces 2020 Jan 08 ;12(1):1404-1411 link
  3. Russelburg LP, O’Shea Murray VL, Demir M, Knutsen KR, Sehgal SL, Cao S, David SS, Horvath MP. “Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.” ACS chemical biology 2020 Jan 17 ;15(1):93-102 link
  4. Berry KN, Brett TJ. “Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement.” Cell reports 2020 Jan 28 ;30(4):1141-1151.e3 link
  5. Smith IW, d’Aquino AE, Coyle CW, Fedanov A, Parker ET, Denning G, Spencer HT, Lollar P, Doering CB, Spiegel PC. “The 3.2 Å structure of a bioengineered variant of blood coagulation factor VIII indicates two conformations of the C2 domain.” Journal of thrombosis and haemostasis : JTH 2020 Jan ;18(1):57-69 link
  6. Tsai CL, Tripp P, Sivabalasarma S, Zhang C, Rodriguez-Franco M, Wipfler RL, Chaudhury P, Banerjee A, Beeby M, Whitaker RJ, Tainer JA, Albers SV. “The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility.” Nature microbiology 2020 Jan ;5(1):216-225 link
  7. Topolska-Woś AM, Sugitani N, Cordoba JJ, Le Meur KV, Le Meur RA, Kim HS, Yeo JE, Rosenberg D, Hammel M, Schärer OD, Chazin WJ. “A key interaction with RPA orients XPA in NER complexes.” Nucleic acids research 2020 Feb 28 ;48(4):2173-2188 link
  8. Stachowski TR, Snell ME, Snell EH. “Structural insights into conformational switching in latency-associated peptide between transforming growth factor β-1 bound and unbound states.” IUCrJ 2020 Mar 01 ;7(Pt 2):238-252 link
  9. Wei KY, Moschidi D, Bick MJ, Nerli S, McShan AC, Carter LP, Huang PS, Fletcher DA, Sgourakis NG, Boyken SE, Baker D. “Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.” Proceedings of the National Academy of Sciences of the United States of America 2020 Mar 31 ;117(13):7208-7215 link
  10. Chandrasekharan NP, Ravenburg CM, Roy IR, Monroe JD, Berndsen CE. “Solution structure and assembly of β-amylase 2 from Arabidopsis thaliana.” Acta crystallographica. Section D, Structural biology 2020 Apr 01 ;76(Pt 4):357-365 link
  11. Zandarashvili L, Langelier MF, Velagapudi UK, Hancock MA, Steffen JD, Billur R, Hannan ZM, Wicks AJ, Krastev DB, Pettitt SJ, Lord CJ, Talele TT, Pascal JM, Black BE. “Structural basis for allosteric PARP-1 retention on DNA breaks.” Science (New York, N.Y.) 2020 Apr 03 ;368(6486):eaax6367 link
  12. Chen Z, Kibler RD, Hunt A, Busch F, Pearl J, Jia M, VanAernum ZL, Wicky BIM, Dods G, Liao H, Wilken MS, Ciarlo C, Green S, El-Samad H, Stamatoyannopoulos J, Wysocki VH, Jewett MC, Boyken SE, Baker D. “De novo design of protein logic gates.” Science (New York, N.Y.) 2020 Apr 03 ;368(6486):78-84 link
  13. Gorelik A, Illes K, Nagar B. “Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme.” Structure (London, England : 1993) 2020 Apr 07 ;28(4):426-436.e3 link
  14. Brunette TJ, Bick MJ, Hansen JM, Chow CM, Kollman JM, Baker D. “Modular repeat protein sculpting using rigid helical junctions.” Proceedings of the National Academy of Sciences of the United States of America 2020 Apr 21 ;117(16):8870-8875 link
  15. Oh DY, Matsumoto Y, Kitajiri SI, Kim NKD, Kim MY, Kim AR, Lee M, Lee C, Tomkinson AE, Katsuno T, Kim SY, Shin HW, Han JH, Lee S, Park WY, Choi BY. “POLD1 variants leading to reduced polymerase activity can cause hearing loss without syndromic features.” Human mutation 2020 May ;41(5):913-920 link
  16. Laciak AR, Korasick DA, Gates KS, Tanner JJ. “Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.” Journal of inherited metabolic disease 2020 May ;43(3):635-644 link
  17. Remesh SG, Verma SC, Chen JH, Ekman AA, Larabell CA, Adhya S, Hammel M. “Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling.” Nature communications 2020 Jun 09 ;11(1):2905 link
  18. Crickard JB, Moevus CJ, Kwon Y, Sung P, Greene EC. “Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination.” Cell 2020 Jun 11 ;181(6):1380-1394.e18 link
  19. Schellenberg MJ, Appel CD, Riccio AA, Butler LR, Krahn JM, Liebermann JA, Cortés-Ledesma F, Williams RS. “Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.” Nucleic acids research 2020 Jun 19 ;48(11):6310-6325 link
  20. DuPrez K, He F, Chen Z, Hilario E, Fan L. “Structural basis of the XPB-Bax1 complex as a dynamic helicase-nuclease machinery for DNA repair.” Nucleic acids research 2020 Jun 19 ;48(11):6326-6339 link
  21. Tsutakawa SE, Sarker AH, Ng C, Arvai AS, Shin DS, Shih B, Jiang S, Thwin AC, Tsai MS, Willcox A, Her MZ, Trego KS, Raetz AG, Rosenberg D, Bacolla A, Hammel M, Griffith JD, Cooper PK, Tainer JA. “Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations.” Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 23 ;117(25):14127-14138 link
  22. Marcum RD, Reyes AA, He Y. “Structural Insights into the Evolutionarily Conserved BAF Chromatin Remodeling Complex.” Biology 2020 Jun 30 ;9(7):146 link
  23. Kumar J, Kaur G, Ren R, Lu Y, Lin K, Li J, Huang Y, Patel A, Barton MC, Macfarlan T, Zhang X, Cheng X. “KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells.” NAR cancer 2020 Jun ;2(2):zcaa007 link
  24. Seacrist CD, Kuenze G, Hoffmann RM, Moeller BE, Burke JE, Meiler J, Blind RD. “Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function.” Structure (London, England : 1993) 2020 Jul 07 ;28(7):830-846.e9 link
  25. Brambley CA, Bolay AL, Salvo H, Jansch AL, Yared TJ, Miller JM, Wallen JR, Weiland MH. “Structural Characterization of Sphingomonas sp. KT-1 PahZ1-Catalyzed Biodegradation of Thermally Synthesized Poly(aspartic acid).” ACS Sustainable Chemistry & Engineering 2020 Jul 13
  26. Sloutsky R, Dziedzic N, Dunn MJ, Bates RM, Torres-Ocampo AP, Boopathy S, Page B, Weeks JG, Chao LH, Stratton MM. “Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation.” Science signaling 2020 Jul 21 ;13(641):eaaz0240 link
  27. Bhargava HK, Tabata K, Byck JM, Hamasaki M, Farrell DP, Anishchenko I, DiMaio F, Im YJ, Yoshimori T, Hurley JH. “Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex.” Proceedings of the National Academy of Sciences of the United States of America 2020 Jul 21 ;117(29):17003-17010 link
  28. Jiao L, Shubbar M, Yang X, Zhang Q, Chen S, Wu Q, Chen Z, Rizo J, Liu X. “A partially disordered region connects gene repression and activation functions of EZH2.” Proceedings of the National Academy of Sciences of the United States of America 2020 Jul 21 ;117(29):16992-17002 link
  29. Huang L, Wright M, Yang S, Blachowicz L, Makowski L, Roux B. “Glycine substitution in SH3-SH2 connector of Hck tyrosine kinase causes population shift from assembled to disassembled state.” Biochimica et biophysica acta. General subjects 2020 Jul ;1864(7):129604 link
  30. Ueda G, Antanasijevic A, Fallas JA, Sheffler W, Copps J, Ellis D, Hutchinson GB, Moyer A, Yasmeen A, Tsybovsky Y, Park YJ, Bick MJ, Sankaran B, Gillespie RA, Brouwer PJ, Zwart PH, Veesler D, Kanekiyo M, Graham BS, Sanders RW, Moore JP, Klasse PJ, Ward AB, King NP, Baker D. “Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.” eLife 2020 Aug 04 ;9:e57659 link
  31. Yan NL, Santos-Martins D, Rennella E, Sanchez BB, Chen JS, Kay LE, Wilson IA, Morgan GJ, Forli S, Kelly JW. “Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins.” Bioorganic & medicinal chemistry letters 2020 Aug 15 ;30(16):127356 link
  32. Dominguez-Martin MA, Hammel M, Gupta S, Lechno-Yossef S, Sutter M, Rosenberg DJ, Chen Y, Petzold CJ, Ralston CY, Polívka T, Kerfeld CA. “Structural analysis of a new carotenoid-binding protein: the C-terminal domain homolog of the OCP.” Scientific reports 2020 Sep 23 ;10(1):15564 link
  33. Wyatt JW, Korasick DA, Qureshi IA, Campbell AC, Gates KS, Tanner JJ. “Inhibition, crystal structures, and in-solution oligomeric structure of aldehyde dehydrogenase 9A1.” Archives of biochemistry and biophysics 2020 Sep 30 ;691:108477 link
  34. Xu C, Lu P, Gamal El-Din TM, Pei XY, Johnson MC, Uyeda A, Bick MJ, Xu Q, Jiang D, Bai H, Reggiano G, Hsia Y, Brunette TJ, Dou J, Ma D, Lynch EM, Boyken SE, Huang PS, Stewart L, DiMaio F, Kollman JM, Luisi BF, Matsuura T, Catterall WA, Baker D. “Computational design of transmembrane pores.” Nature 2020 Sep ;585(7823):129-134 link
  35. Banda DM, Pereira JH, Liu AK, Orr DJ, Hammel M, He C, Parry MAJ, Carmo-Silva E, Adams PD, Banfield JF, Shih PM. “Novel bacterial clade reveals origin of form I Rubisco.” Nature plants 2020 Sep ;6(9):1158-1166 link
  36. Eckelmann BJ, Bacolla A, Wang H, Ye Z, Guerrero EN, Jiang W, El-Zein R, Hegde ML, Tomkinson AE, Tainer JA, Mitra S. “XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells.” NAR cancer 2020 Sep ;2(3):zcaa013 link
  37. Zeng Y, Ren R, Kaur G, Hardikar S, Ying Z, Babcock L, Gupta E, Zhang X, Chen T, Cheng X. “The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation.” Genes & development 2020 Nov 01 ;34(21-22):1546-1558 link
  38. Thapar R, Wang JL, Hammel M, Ye R, Liang K, Sun C, Hnizda A, Liang S, Maw SS, Lee L, Villarreal H, Forrester I, Fang S, Tsai MS, Blundell TL, Davis AJ, Lin C, Lees-Miller SP, Strick TR, Tainer JA. “Mechanism of efficient double-strand break repair by a long non-coding RNA.” Nucleic acids research 2020 Nov 04 ;48(19):10953-10972 link
  39. Pinals RL, Yang D, Rosenberg DJ, Chaudhary T, Crothers AR, Iavarone AT, Hammel M, Landry MP. “Quantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological Environments.” Angewandte Chemie (International ed. in English) 2020 Dec 21 ;59(52):23668-23677 link
  40. Reyes-Aldrete E, Dill EA, Bussetta C, Szymanski MR, Diemer G, Maindola P, White MA, Bujalowski WM, Choi KH, Morais MC. “Biochemical and Biophysical Characterization of the dsDNA Packaging Motor from the Lactococcus lactis Bacteriophage Asccphi28.” Viruses 2020 Dec 23 ;13(1):15 link
  41. Uhlemann EE, Yu CH, Patry J, Dolgova N, Lutsenko S, Muyldermans S, Dmitriev OY. “Nanobodies against the metal binding domains of ATP7B as tools to study copper transport in the cell.” Metallomics : integrated biometal science 2020 Dec 23 ;12(12):1941-1950 link
  42. Stachowski TR, Snell ME, Snell EH. “SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique.” PloS one 2020 ;15(11):e0239702 link
  43. Weinhardt V, Chen JH, Ekman AA, Guo J, Remesh SG, Hammel M, McDermott G, Chao W, Oh S, Le Gros MA, Larabell CA. “Switchable resolution in soft x-ray tomography of single cells.” PloS one 2020 ;15(1):e0227601 link
  44. Walker RG, Kattamuri C, Goebel EJ, Zhang F, Hammel M, Tainer JA, Linhardt RJ, Thompson TB. “Heparin-mediated dimerization of follistatin.” Experimental biology and medicine (Maywood, N.J.) 2021 Feb ;246(4):467-482 link
  45. Lees-Miller JP, Cobban A, Katsonis P, Bacolla A, Tsutakawa SE, Hammel M, Meek K, Anderson DW, Lichtarge O, Tainer JA, Lees-Miller SP. “Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease.” Progress in biophysics and molecular biology 2021 Aug ;163:87-108 link
  46. Hammel M, Rosenberg DJ, Bierma J, Hura GL, Thapar R, Lees-Miller SP, Tainer JA. “Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM.” Progress in biophysics and molecular biology 2021 Aug ;163:74-86 link

More publication years

© 2026 The SIBYLS Beamline. Built using WordPress and Mesmerize Theme.