SIBYLS Beamline

Brought to you by IDAT, SBDR, ALS-ENABLE, and the DOE

Highlights and Announcements

8th DNA Repair/Replication Structures & Cancer Conference: Nov 7 – Nov 10, 2027 in Playa Mujeres, Mexico

SIBYLS Beamline members and users will speak at the 8th DNA Replication/Repair Structures & Cancer Conference (8th DRRSC) in November 2027. This conference aims to translate hybrid structural biology into biological and[…]

Read more

Exploring the impact of nucleotide length on lipid nanoparticle structure and properties

Using SAXS, supported by cryo-EM, SIBYLS scientists along with researchers at Genentech gained insights into the impact of nucleotide length on lipid nanoparticle structure and properties. LNPs serve as a[…]

Read more

BilboMD: a web-accessible SAXS and AlphaFold-guided modeling pipeline

BilboMD is a web-based application developed and hosted by the SIBYLS beamline staff offering accessible pipelines for the analysis of SAXS data, including conformational sampling through molecular dynamics simulations, SAXS[…]

Read more

Structure–Function Relationships in Sequence-Controlled Copolymers for Rare Earth Element Chelation

In this publication led by Abigail Knight, an Assistant Professor of Chemistry at UNC-Chapel Hill and a SIBYLS SAXS user, the authors report on systematic research into amphiphilic polymer chelators,[…]

Read more