Fast SAXS profile computation with Debye formula
FoXS, a new webapp which uses the Debye formula for calculating theoretical scattering profiles, has been made available on the ModBase website. Give it a try to see how it compares to CRYSOL.
FoXS is a method for computing a theoretical scattering profile of a structure and fitting of experimental profile. FoXS can be used as a basic tool for numerous structural modeling applications with SAXS data:
- Comparison of solution and X-ray structure conformations
- Modeling of different conformation, i.e. model active conformation starting from non-active
- Structural characterization of flexible proteins
- Assembly of multi domain proteins starting from single domain structures
- Assembly of multi protein complexes
- Fold recognition and comparative modeling
- Determination of biologically relevant state from the crystals