Hello DOMO users, [DOMO](http://bl1231.als.lbl.gov/domo/) is fairly robust, and is capable of handling your precious crystals mounted in a variety of bases: However, you must take some care when gluing or epoxying the pins into the bases. If there is too much glue or epoxy or you inadvertantly get some on the sides or bottom of…
Read more
The SIBYLS beamline has recently been awarded 50,000 hours on the NERSC (National Energy Research Scientific Computing Center) to perform solution structure modeling using experimental SAXS data. Besides the usual ab-initio reconstructions programs a new approach in rigid body modeling BILBOMD has been parallelized on the NERSC supercomputer. It is commonly acknowledged that flexibility between domains of…
Read more
a resource for HTS of crystallization conditions.
[Quen Cheng](mailto:QJCheng@lbl.gov) in the Cooper lab has done a nice set of [experiments](http://bl1231.als.lbl.gov/saxs_protocols/saxs_detergents.php) to address the usefulness of various readily available detergents for improving the behavior proteins in SAXS experiments.
A new review on macromolecular SAXS has been published in the Quarterly Reviews in Biophysics by *Putnam, C.D., Hammel, M., Hura, G.L., and Tainer, J.A.* >”This six part review addresses both theoretical and practical concepts, concerns and considerations for using these techniques in conjunction with computational methods to productively combine solution scattering data with high-resolution…
Read more