Category: Science Highlights

Yeast Topoisomerase II bound to DNA

As recently [reported](http://www-als.lbl.gov/als/science/sci_archive/160topoII.html) in the ALSNews: > “The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication and is a prime target of antibacterial and anticancer drugs. Researchers at Berkeley Lab and the University of California, Berkeley, have produced the first three-dimensional structural images of…
Read more

Publications in 2007

At least 18 publications were made possible by the SIBYLS beamline in 2007 and have been added to our [publications](http://bl1231.als.lbl.gov/publications/index.php) page. We are very pleased that the PX and SAXS endstations have been so useful to so many researchers doing such varied work. We hope that 2008 will be even more productive. If you know…
Read more

Structure of a Thermus thermophilus 70S ribosome functional complex at 3.7 Å resolution

In 2006 the Noller lab from the University of California, Santa Cruz solved the structure of the Thermus thermophilus 70S ribosome at 3.7Å resolution. This work was supported by data collected at both 12.3.1 and has been recently highlighted in the ALS news. The original publication was in CELL. Korostelev A, Trakhanov S, Laurberg M,…
Read more