Tag: MX

The point-spread function of fiber-coupled area detectors

A recent IDAT [publication](http://dx.doi.org/10.1107/S0909049512035571) from James, Chris, and Ken investigating the source of the point spread function in detectors using CCDs coupled fiber optic tapers. >The point-spread function (PSF) of a fiber-optic taper-coupled CCD area detector was measured over five decades of intensity using a 20 µm X-ray beam and 2000-fold averaging. The “tails” of…
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Structure of XLF-XRCC4 Provides Model for Double Strand Break Repair

DNA double strand break repair via nonhomologous end joining is a critical regulatory function that maintains genomic integrity. One of the major factors involved in this process is the XLF-XRCC4 protein complex. Although mutation of either XLF or XRCC4 leads to defects in break repair, the function of the XLF-XRCC4 complex has remained enigmatic. In…
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